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United Kingdom2 days leftOpen

Supply of A high resolution mass spectrometer

Tender Overview

LOCATION

Tees Valley and Durham, United Kingdom

VALUE

Not disclosed

DEADLINE

February 03, 2026 at 23:59

CATEGORY

Other

CPV CODE

38000000

REFERENCE

001397-2026

Project Timeline

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Contact Information

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Original Tender Description

The identification and validation of cancer biomarkers requires highly sensitive and robust analytical technologies capable of delivering deep proteome coverage, reproducible quantitation, and confident peptide and protein identification. To support ongoing research in the next generation diagnostic programme at CPI Biologics, Darlington, supporting application to clinical proteomics, there is a need to procure a LC-MS system specifically optimised for advanced proteomics applications. The LC-MS instrument will underpin discovery-to-validation workflows in cancer biomarker research, enabling both untargeted and targeted proteomics approaches within a single platform. It must demonstrate proven performance in single-cell proteomics, clinical proteomics, host cell protein analysis, and post-translational modification studies, with published evidence supporting its application in these domains. High resolution, sensitivity, dynamic range, and throughput are critical to ensure reliable detection of low-abundance proteins and post-translational modifications that are central to biomarker discovery. The acquisition of this LC-MS system will provide the necessary technological foundation to accelerate biomarker discovery, improve clinical translation, and strengthen CPIs capabilities in proteomics.
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MANDATORY EXCLUSION GROUNDS

  • No specific mandatory exclusion grounds are provided in the tender information.
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ELIGIBILITY REQUIREMENTS

  • No specific eligibility requirements are provided in the tender information.
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TECHNICAL CAPABILITY REQUIREMENTS

  • Supply a high-resolution mass spectrometer.
  • Supply an LC-MS system specifically optimised for advanced proteomics applications.
  • The system must be capable of delivering deep proteome coverage.
  • The system must be capable of reproducible quantitation.
  • The system must be capable of confident peptide and protein identification.
  • The LC-MS instrument must underpin discovery-to-validation workflows in cancer biomarker research.
  • The system must enable both untargeted and targeted proteomics approaches within a single platform.
  • The system must demonstrate proven performance in single-cell proteomics.
  • The system must demonstrate proven performance in clinical proteomics.
  • The system must demonstrate proven performance in host cell protein analysis.
  • The system must demonstrate proven performance in post-translational modification studies.
  • Provide published evidence supporting the system's application in single-cell proteomics, clinical proteomics, host cell protein analysis, and post-translational modification studies.
  • The system must have high resolution.
  • The system must have high sensitivity.
  • The system must have a high dynamic range.
  • The system must have high throughput.
  • The system must ensure reliable detection of low-abundance proteins.
  • The system must ensure reliable detection of post-translational modifications.
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FINANCIAL REQUIREMENTS

  • No specific financial requirements are provided in the tender information.
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SUBMISSION REQUIREMENTS

  • Submit the bid by 2026-02-03 23:59:59.

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PDF
Official PDF Version
PDF001397-2026_official.pdf
Summary:
This tender seeks a high-resolution LC-MS system for advanced proteomics in cancer biomarker research, requiring proven performance in specific proteomic applications and will be procured via a single-supplier framework allowing direct awards.

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68
Good

Tender Quality Score

This tender presents a clear technical need for a high-resolution mass spectrometer with an innovation focus, but suffers from significant transparency and fairness issues due to classified value, missing evaluation criteria, and highly specific requirements.

Score Breakdown

Legal Compliance75/100

The tender correctly defines the procedure type and CPV codes, and there are no reported disputes. The 16-day period from today's date to the submission deadline is reasonable. However, the estimated value is classified, and the reveal date is missing, which are transparency concerns.

•Value not disclosed (classified)
•Missing reveal date
Clarity80/100

The technical description of the required LC-MS system and its applications is exceptionally clear and detailed. The AI-extracted technical requirements are also precise and well-documented. A significant drawback is the complete absence of specified evaluation criteria, which leaves bidders without clear guidance on how their proposals will be assessed.

•No evaluation criteria specified
Completeness70/100

Basic information, deadlines, and contract duration are provided. Technical requirements are well-defined. However, the estimated value is classified, and crucially, evaluation criteria are entirely missing, which are major omissions for a comprehensive tender document.

•Value not disclosed (classified)
•Missing evaluation criteria
Fairness40/100

The classified estimated value and the complete lack of evaluation criteria severely undermine transparency and fairness for potential bidders. The absence of e-submission also creates an unequal playing field. Furthermore, the highly specific technical requirements, demanding 'proven performance' and 'published evidence' in multiple niche proteomics applications, strongly suggest the tender may be tailored to a very limited number of high-end manufacturers, significantly restricting competition.

•Value not disclosed (classified)
•Missing evaluation criteria
Practicality65/100

The tender specifies a contract start date and duration. However, the lack of electronic submission is a practical inconvenience, and the classified estimated value makes it difficult for bidders to gauge the scope and prepare appropriate financial proposals.

•No e-submission
•Value not disclosed (classified)
Data Consistency90/100

Most key fields are populated, and dates are logical and consistent. There are no reported suspensions or disputes. Minor inconsistencies include an empty 'Liable Person' field and N/A codes for procedure type.

•Liable Person not specified
•N/A codes for procedure type
Sustainability50/100

The tender explicitly mentions an 'Innovation Focus' which is a positive aspect. However, it lacks any specified green procurement or social criteria, and it is not EU funded, indicating limited broader sustainability considerations.

•Not green procurement
•No social criteria

Strengths

Clear and detailed technical description of the required system
Specific and comprehensive technical capability requirements
Innovation focus explicitly stated
Defined procedure type and appropriate CPV code
Logical and consistent timeline data

Concerns

Absence of evaluation criteria, severely impacting clarity and fairness
Estimated value is classified, reducing transparency and hindering bid preparation
Highly specific technical requirements, potentially limiting competition to a few suppliers
Lack of electronic submission support
No green procurement or social criteria included

Recommendations

1. Publish clear and objective evaluation criteria to ensure transparency and fairness.
2. Disclose the estimated value to assist bidders in preparing realistic proposals.
3. Implement electronic submission for improved accessibility and efficiency.

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Tender Quality Score
68/ 100 · Good
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